Estrogen driven breast cancer


The AIs tend to have fewer serious side effects than tamoxifen. They are often continued for as long as they are helpful. A test called an immunohistochemistry or IHC is used most often to find out if cancer cells have estrogen and progesterone receptors. Some women with cancer spread to the bones may have a tumor flare with pain and swelling in the muscles and bones. This drug is not a SERM — it acts like an anti-estrogen throughout the body.
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Hormone Receptor Status

DCIS should be checked for hormone receptors, too. If the cancer is hormone-receptor-negative no receptors are present , then hormonal therapy is unlikely to work. This may allow some other hormone therapies, such as AIs, to be used. Cancers are called hormone receptor-positive or hormone receptor-negative based on whether or not they have these receptors proteins. Test results will give you your hormone receptor status.
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Hormone Therapy for Breast Cancer

Because of this, it is called a selective estrogen receptor modulator SERM. The test results will help guide you and your cancer care team in making the best treatment decisions. Fulvestrant is currently approved only for use in post-menopausal women. Breast cancer cells taken out during a biopsy or surgery will be tested to see if they have certain proteins that are estrogen or progesterone receptors. Chemotherapy can still be useful. It is not likely to work if tamoxifen has already been used and has stopped working.
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Description:It is given by injections into the buttocks. About 2 of 3 breast cancers have at least one of these receptors. Another option is taking a drug called a luteinizing hormone-releasing hormone LHRH analog, which turns off the ovaries, along with an AI. These cancers tend to grow faster than hormone receptor-positive cancers. If the cancer is hormone-receptor-negative no receptors are present , then hormonal therapy is unlikely to work. Hormone receptor-positive cancers tend to grow more slowly than those that are hormone receptor-negative.

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