Chemotherapy drugs that affect cells when they are at rest are called cell-cycle non-specific. Supplemental Content Full text links. Generate a file for use with external citation management software. Antitumor antibiotics are made from natural products produced by species of the soil fungus Streptomyces. Sign Up It's Free! The ability of chemotherapy to kill cancer cells depends on its ability to halt cell division. Breast cancer — both invasive and non-invasive — was diagnosed in about , women and 2, men in in the U.
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Role of epirubicin in advanced breast cancer.
Didn't get the message? Epub Jan Chemotherapy drugs that affect cells only when they are dividing are called cell-cycle specific. Breast cancer treatment is divided into two categories. It is indicated as a component of adjuvant therapy in patients with evidence of axillary node tumor involvement for primary breast cancer, which means that it is used in breast cancer patients whose tumors have spread to the lymph nodes and have had surgery.
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Epirubicin: is it like doxorubicin in breast cancer? A clinical review.
The anthracyclines commonly used in treatment of breast cancer are either epirubicin or doxorubicin. This medication is classified as an "anthracyline antitumor antibiotic. A must-read every morning. Medscape App Get fast, accurate answers for point-of-care decision making. Anthracyclines were first introduced for the treatment of metastatic breast cancer in the s and are still among the most active single agents for the treatment of this disease. The faster the cells are dividing, the more likely it is that chemotherapy will kill the cells, causing the tumor to shrink. Your fertility, meaning your ability to conceive or father a child, may be affected by epirubicin.
Description:This review summarizes published clinical trials investigating epirubicin in the treatment of early and advanced breast cancer. Cancerous tumors are characterized by cell division, which is no longer controlled as it is in normal tissue. Antitumor antibiotics are made from natural products produced by species of the soil fungus Streptomyces. Supplemental Content Full text links. Get helpful advice on your cases from a community of physicians. Cancerous cells lose this ability.